Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 25;19:197. doi: 10.1186/s12985-022-01912-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 1 — Assessment of antibody responses against SARS-CoV-2 in unvaccinated individuals and vaccinees from Omicron-BA.2 infection

(A-B) Kinetics of anti-RBD IgM antibody titers of sera from Omicron-infected individuals (A) and Wuhan strain-infected individuals (B) against SARS-CoV-2 Wuhan strain and Omicron-BA.2 strain during 7–27 days after onset using the ELISA assay. (C) Kinetics of anti-RBD IgG antibody titers of sera from Omicron-infected individuals against SARS-CoV-2 Wuhan strain and Omicron-BA.2 strain during 7–27 days after onset using the ELISA assay.The titers were calculated at 450nm (OD50), and serum samples from 7 days, 8 to 14 days, 15 to 21 days, and 22 to 27 days after onset were tested respectively. (D-F) Dynamic change of anti-RBD IgM and IgG antibody titers against SARS-CoV-2 Wuhan strain and Omicron-BA.2 strain in vaccinees of inactivated COVID-19 vaccine (panel D) or unvaccinated individuals (panel E) or all COVID − 19 patients (panel F) in the 0–7 days or 8–27 days after onset. (G-I) Dynamic change of neutralization antibody titers against authentic SARS-CoV-2 Wuhan strain and Omicron-BA.2 variant in vaccinees of inactivated COVID-19 vaccine (panel G) or unvaccinated individuals (panel H) or all COVID − 19 patients (panel I) in the 0–7 days or 8–27 days after onset. Geometric mean titers (GMT) of neutralizing antibodies were shown. The sample size for each panel was shown as n. P values were obtained from a comparison between the two treatment groups using t-tests for long-transformed antibodies or two-sided χ2 tests for categorical data. Multiple comparisons of antibody titers were performed using the Welch’ t-test