Table 2.
Surgery, perioperative, and postoperative outcomes
| Variable | n (%)/[range] | P value |
|---|---|---|
| Surgery, (VATS) | 0.603 | |
| Lobectomy | 14 (73.7) | |
| n= RUL/RML/RLL/LUL/LLL | 3/1/5/2/3 | |
| Sublobar resection | 5 (26.3) | |
| n=Trisegmentectomy/lingulectomy/subsegmentectomy/Wedge resection | 2/1/1/1 | |
| Number of lymphadenectomy, median | 20 [5-38] | |
| Complete resection | 1.000 | |
| R0 | 17 (89.5) | |
| R2 | 2 (10.5) | |
| Duration of surgery, median minutes | 180 [60-380] | 0.020 |
| Blood loss, median ml | 40 [10-550] | 0.049 |
| Postoperative complications | 0.614 | |
| Bleeding | 1 (5.3) | |
| Thoracic empyema | 1 (5.3) | |
| Nil | 17 (89.5) | |
| 30-day postoperative mortality | 0 (0) | |
| Median time to relapse, months | 13 [6-41] | |
| Relapse | <0.001 | |
| Alive without relapse | 10 (52.6) | |
| Alive with relapse | 2 (10.5) | |
| Died with relapse | 7 (36.8) | |
| T790M status | ||
| Positive | 1 (5.3) | |
| Negative | 1 (5.3) | |
| Unknown/not done | 17 (89.4) | |
| Recurrence pattern | <0.001 | |
| Intrathoracic recurrence/metastases | 2 (10.5) | |
| Distant metastases | 3 (15.8) | |
| Intrathoracic and distant metastases | 4 (21.1) | |
| Nil | 10 (52.6) | |
| Postoperative adjuvant therapy | 0.129 | |
| TKI | 13 (68.4) | |
| Non-TKI | 6 (31.6) |
VATS video-assisted thoracoscopic surgery, RUL right upper lobe, RML right middle lobe, RLL right lower lobe, LUL left upper lobe, LLL left lower lobe, TKI tyrosine-kinase inhibitor