Table 2.
The effects of GPEs on SCE and MN rates in cultured human lymphocytes. ∗symbol presents a statistical difference from the control (-) group at the level of p < 0.05.
| Groups | SCEs/cell | MN/2000 cells | Nuclear division index (NDI) |
|---|---|---|---|
| Untreated cells | 4.55 ± 0.78 | 0.91 ± 0.15 | 1.37 ± 0.26 |
| MMC | 10.92 ± 1.06∗ | 3.74 ± 0.52∗ | 1.09 ± 0.21∗ |
|
| |||
| GPE | |||
| 0.1 μM | 4.16 ± 0.61 | 0.79 ± 0.18 | 1.38 ± 0.22 |
| 1 μM | 4.06 ± 0.59 | 0.83 ± 0.22 | 1.42 ± 0.14 |
| 10 μM | 4.38 ± 0.41 | 0.88 ± 0.15 | 1.39 ± 0.31 |
| 25 μM | 4.46 ± 0.73 | 0.85 ± 0.19 | 1.36 ± 0.25 |
| 50 μM | 4.41 ± 0.36 | 0.89 ± 0.20 | 1.34 ± 0.24 |
| 100 μM | 4.47 ± 0.63 | 0.90 ± 0.18 | 1.32 ± 0.21 |
|
| |||
| GPE1 | |||
| 0.1 μM | 4.29 ± 0.43 | 0.81 ± 0.15 | 1.44 ± 0.29 |
| 1 μM | 4.47 ± 0.55 | 0.84 ± 0.23 | 1.41 ± 0.33 |
| 10 μM | 4.55 ± 0.69 | 0.90 ± 0.22 | 1.37 ± 0.23 |
| 25 μM | 4.52 ± 0.56 | 0.94 ± 0.17 | 1.34 ± 0.28 |
| 50 μM | 4.63 ± 0.48 | 0.98 ± 0.21 | 1.32 ± 0.22 |
| 100 μM | 4.65 ± 0.53 | 1.02 ± 0.24 | 1.42 ± 0.24 |
|
| |||
| GPE2 | |||
| 0.1 μM | 4.38 ± 0.36 | 0.85 ± 0.13 | 1.38 ± 0.30 |
| 1 μM | 4.51 ± 0.50 | 0.89 ± 0.19 | 1.37 ± 0.25 |
| 10 μM | 4.58 ± 0.47 | 0.91 ± 0.16 | 1.34 ± 0.27 |
| 25 μM | 4.66 ± 0.60 | 0.92 ± 0.26 | 1.30 ± 0.33 |
| 50 μM | 4.69 ± 0.51 | 1.01 ± 0.23 | 1.28 ± 0.27 |
| 100 μM | 4.71 ± 0.66 | 1.04 ± 0.20 | 1.22 ± 0.24 |
|
| |||
| GPE3 | |||
| 0.1 μM | 4.18 ± 0.44 | 0.77 ± 0.17 | 1.45 ± 0.29 |
| 1 μM | 4.29 ± 0.51 | 0.76 ± 0.21 | 1.43 ± 0.26 |
| 10 μM | 4.23 ± 0.40 | 0.82 ± 0.24 | 1.41 ± 0.31 |
| 25 μM | 4.35 ± 0.36 | 0.85 ± 0.16 | 1.42 ± 0.34 |
| 50 μM | 4.45 ± 0.56 | 0.88 ± 0.28 | 1.40 ± 0.27 |
| 100 Μm | 4.61 ± 0.47 | 0.92 ± 0.23 | 1.38 ± 0.25 |