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. 2022 Nov 25;3(11):1300–1317. doi: 10.1038/s43018-022-00450-6

Table 2.

Demographic and clinical characteristics stratified by MPR

MPR (Yes/No) No Yes P
Sex Female 0 (0.0) 6 (50.0) 0.234
Male 4 (100.0) 6 (50.0)
Age (yr) Median (IQR) 58.0 (53.8 to 66.8) 62.5 (57.2 to 69.0) 0.952
Smoking Never smoker 1 (25.0) 3 (25.0) 1.000
Smoker 3 (75.0) 9 (75.0)
Time to surgery (d) Median (IQR) 48.5 (37.5 to 56.5) 46.0 (44.2 to 47.8) 0.951
Radiation dosage 18 3 (75.0) 4 (33.3) 0.262
24 1 (25.0) 8 (66.7)
T stage T2 0 (0.0) 0 (0.0) 0.529
T3 0 (0.0) 3 (25.0)
T4 4 (100.0) 9 (75.0)
N stage N0 0 (0.0) 3 (25.0) 0.769
N1 1 (25.0) 4 (33.3)
N2 3 (75.0) 5 (41.7)
Alcohol history ≤20 yr 0 (0.0) 4 (33.3) 0.209
>20 yr 3 (75.0) 3 (25.0)
No alcohol 0 (0.0) 2 (16.7)
(Missing) 1 (25.0) 3 (25.0)
Location Gingiva 0 (0.0) 3 (25.0) 0.140
Hard palate 0 (0.0) 1 (8.3)
Larynx 0 (0.0) 2 (16.7)
Retromolar Trigone 2 (50.0) 0 (0.0)
Tongue 2 (50.0) 6 (50.0)
Previous RT (yes/no) No 3 (75.0) 9 (75.0) 1.000
Yes 1 (25.0) 3 (25.0)

The associations between MPR and demographic and clinical characteristics were evaluated with two-sided nonparametric Wilcoxon rank sum test for continuous variables, and with two-sided Fisher’s exact test for categorical variables. No multiple comparison adjustment.