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. Author manuscript; available in PMC: 2023 Nov 25.
Published in final edited form as: Chemistry. 2022 Sep 19;28(66):e202201843. doi: 10.1002/chem.202201843

Figure 5.

Figure 5.

Activated Michael acceptors for fast cysteine bioconjugation. aObserved reaction rate constant for N-Boc-Cys-OMe. bObserved reaction rate constant for N-Ac-Cys-NH2. ΔG:Gibbs free energy of activation