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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Curr Opin Microbiol. 2022 Oct 13;70:102222. doi: 10.1016/j.mib.2022.102222

Figure 1. Overview of the skin microbiome.

Figure 1.

A) The skin microbiome in healthy skin is considered to reside primarily in deeper structures such as pilosebaceous units (e.g., terminal or vellus hair follicles and sebaceous glands) and sweat glands, with relatively fewer microbes inhabiting the stratum corneum. Localization, density, and admixture of species within these structures remains little defined. These bacteria, fungi, and viruses have important roles in skin barrier homeostasis, cutaneous innate and adaptive immunity, and help condition the skin microenvironment. B) Representation of major skin microbiome changes over lifespan, where available. Piecharts are composite relative abundance data from the three indicated studies.