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. 2022 Nov 26;5:1299. doi: 10.1038/s42003-022-04274-z

Fig. 1. Enhancing neural activity in the lateral septum.

Fig. 1

a Schematic illustrating animal groups receiving AAV8-hSyn-hM3D-mCherry injections into the LS and 3 mg/kg C21 i.p. injections (hM3 + C21, green, n = 10); AAV8-hSyn-hM3D-mCherry injections into the LS and saline i.p. injections (hM3 + saline, gray, n = 10); or sham injections into the LS and 3 mg/kg C21 i.p. injections (sham + C21, purple, n = 12). b Timeline of experimental design. LS lateral septum, SAT social approach test, RIT resident intruder test, PPT partner preference test. Red dot indicates when hM3Dq-mCherry or sham injection surgeries targeting the LS were performed. Blue dots indicate when 3 mg/kg C21 or saline (i.e., vehicle) were injected (i.p.) 30 min prior to each behavioral assessment.