Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Generation of targeted editing in mouse embryos by NcCas9.
| PAM | Target site | No. of zygotes | No. of blastocysts | No. of editing (%) | Frequencies of editingin single embryo (%) |
|---|---|---|---|---|---|
| N4GTAT | Tyr-1 | 20 | 8 | 2 (25) | (26.1–30.7) |
| Pcsk9-1 | 20 | 10 | 8 (80) | (21.2–98.6) | |
| N4GCAT | Tyr-2 | 20 | 8 | 0 (0) | (0) |
| Pcsk9-2 | 20 | 9 | 0 (0) | (0) |
