Table 2.
Analytical performance of biosensors for IC50 determination of cyclo(RGDyK) or its analogues
| Method | Indicator | Biocompatibility | Assay time | Reference |
|---|---|---|---|---|
| MTT assay | Formazan | Bad | 51 h | 55 |
| CCK-8 assay | Formazan | Bad | 25 h | 62 |
| ELISA | TMB | Good | 4 h | 63 |
| Radioimmunoassay | 125I-labeled echistatin | Bad | 3 h | 56 |
| Chemiluminescence | Galacton-Plus | Bad | 195 min | 64 |
| Fluorescence | Alamar blue | Good | 72 h | 65 |
| ECL | RRGDS-BPQDs | Good16 | 170 min | This work |
MTT (3-(4,5-imethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide, CCK-8 cell counting kit-8, ELISA enzyme linked immune sorbent assay, TMB 3,3’,5,5’-tetramethylbenzidine.