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. 2022 Oct 28;14(10):e30787. doi: 10.7759/cureus.30787

Table 4. GHQ-28 scores at baseline and during study period in PP dataset.

GHQ-28: general health questionnaire-28; PP: per-protocol; CI: confidence interval

  Ashwagandha  (AG, n=37) Placebo  (PL, n=35) t-test Mean  Difference   Effect size (Cohen’s)
  Mean SD Mean SD t' p' 95% C.I. for diff. ‘d' 95% C.I. for ‘d’
Total GHQ-28 score                    
Day 0 53.27 12.25 52.80 10.94 0.171 0.864 0.47 -5.00 to 5.94 0.04 -0.42 to 0.50
Change at Week 8 -7.84 8.74 -3.91 9.87 -1.789 0.078 -3.92 -8.30 to 0.45 -0.42 -0.89 to 0.05
Physical score                    
Day 0 14.14 2.93 12.60 3.37 2.067 0.042 1.54 0.05 to 3.02 0.49 0.02 to 0.95
Change at Week 8 -1.78 3.00 -0.74 3.04 -1.461 0.148 -1.04 -2.46 to 0.38 -0.34 -0.81 to 0.12
Anxiety score                    
Day 0 12.35 4.18 11.77 3.93 0.606 0.546 0.58 -1.33 to 2.49 0.14 -0.32 to 0.61
Change at Week 8 -2.95 3.83 -1.54 5.77 -1.222 0.226 -1.40 -3.69 to 0.89 -0.29 -0.75 to 0.18
Social function score                    
Day 0 13.92 3.17 14.29 2.61 -0.535 0.594 -0.37 -1.73 to 1.00 -0.13 -0.59 to 0.34
Change at Week 8 -1.76 3.38 -0.83 3.02 -1.226 0.224 -0.93 -2.44 to 0.58 -0.29 -0.75 to 0.18
Depression score                    
Day 0 12.86 3.54 14.14 2.59 -1.741 0.086 -1.28 -2.74 to 0.19 -0.41 -0.88 to 0.06
Change at Week 8 -1.35 3.15 -0.80 3.35 -0.720 0.474 -0.55 -2.08 to 0.98 -0.17 -0.63 to 0.29