Table 2.
Summary of DHA-PPQ resistance markers in test samples
| Isolate ID | Year of collection | Kelch13 SNPs |
Plasmepsin-2 CNV |
Pfcrt SNPs | ||||
|---|---|---|---|---|---|---|---|---|
| Copy number | Classification | Exon 2 | Exon 3 | |||||
| T93S | H97Y | F145I | Other | |||||
| 1 | 2013 | C580Y | 1.2 | Single | T93 | H97 | F145 | No SNPs |
| 2 | 2013 | C580Y | 0.7 | Single | T93 | H97 | F145 | No SNPs |
| 3 | 2014 | – | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 4 | 2014 | No SNPs | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 5 | 2014 | No SNPs | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 6 | 2014 | No SNPs | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 7 | 2014 | R659R | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 8 | 2014 | C580Y | 1.3 | Single | T93 | H97 | F145 | No SNPs |
| 9 | 2014 | C580Y | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 10 | 2014 | No SNPs | 0.6 | Single | T93 | H97 | F145 | No SNPs |
| 11 | 2014 | No SNPs | 1.2 | Single | T93 | H97 | F145 | No SNPs |
| 12 | 2014 | No SNPs | 1.2 | Single | T93 | H97 | F145 | No SNPs |
| 13 | 2014 | No SNPs | 1.2 | Single | - | - | F145 | No SNPs |
| 14 | 2014 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 15 | 2014 | G538V | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 16 | 2014 | G533S | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 17 | 2014 | G533S | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 18 | 2014 | No SNPs | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 19 | 2014 | No SNPs | 1.3 | Single | T93 | H97 | – | – |
| 20 | 2014 | G533S | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 21 | 2014 | G533S | 1.3 | Single | T93 | H97 | F145 | No SNPs |
| 22 | 2014 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 23 | 2014 | No SNPs | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 24 | 2015 | G533S | 1.0 | Single | – | – | F145 | No SNPs |
| 25 | 2015 | G533S | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 26 | 2015 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 27 | 2015 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 28 | 2015 | G533S | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 29 | 2015 | No SNPs | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 30 | 2015 | – | 1.4 | Single | T93 | H97 | F145 | No SNPs |
| 31 | 2015 | G533S | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 32 | 2015 | G538V | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 33 | 2015 | No SNPs | – | – | T93 | H97 | – | – |
| 34 | 2015 | G533S | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 35 | 2015 | G533S | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 36 | 2015 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 37 | 2015 | No SNPs | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 38 | 2015 | No SNPs | 0.5 | Single | T93 | H97 | F145 | No SNPs |
| 39 | 2015 | No SNPs | 0.9 | Single | - | - | F145 | No SNPs |
| 40 | 2015 | No SNPs | 1.2 | Single | T93 | H97 | F145 | No SNPs |
| 41 | 2015 | G533S | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 42 | 2016 | No SNPs | 1.2 | Single | T93 | H97 | F145 | No SNPs |
| 43 | 2018 | G533S | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 44 | 2018 | No SNPs | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 45 | 2018 | C580Y | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 46 | 2018 | C580Y | 1.1 | Single | T93 | H97 | F145 | No SNPs |
| 47 | 2018 | G533S | – | – | – | – | – | – |
| 48 | 2018 | G533S | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 49 | 2019 |
G533S A564A |
– | – | – | – | 145I | S140P |
| 50 | 2019 | G533S | – | – | T93 | H97 | F145 | No SNPs |
| 51 | 2019 | G533S | 1.0 | Single | T93 | H97 | F145 | No SNPs |
| 52 | 2019 | G533S | – | – | T93 | H97 | F145 | No SNPs |
| 53 | 2019 | G533S | 0.9 | Single | T93 | H97 | F145 | No SNPs |
| 54 | 2019 | G533S | – | – | T93 | H97 | F145 | No SNPs |
| 55 | 2019 | G533S | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 56 | 2019 | G533S | 0.8 | Single | T93 | H97 | F145 | No SNPs |
| 57 | 2019 | G533S | 1.1 | Single | T93 | H97 | F145 | No SNPs |
No data