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. 2022 Nov 26;10:170. doi: 10.1186/s40478-022-01475-9

Table 2.

Summary of r-mTBI and PFF induced PD like pathology in the SNpc

Left Right
pTau aSyn TH loss Iba1 + MHCII pTau aSyn TH loss Iba1 + MHCII
8× r-mTBI + PFF +++ 0 0 +++ +++ +++ ++ +++
PFF + 0 0 0 +++ +++ ++ ++
8× r-mTBI + Mono +++ 0 0 +++ +++ 0 0 +++
8× r-mTBI +++ 0 0 +++ +++ 0 0 +++
4× r-mTBI + 0 0 0 + 0 0 0
Sham + 0 0 0 + 0 0 0

Relative abundance of pathology is listed in descending order of burden in the left and the right side of the brain. For rats that underwent intracranial injection, right side is ipsilateral to the injection