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. 2022 Oct 4;6(12):3550–3562. doi: 10.1002/hep4.2106

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© 2022 The Authors. Hepatology Communications published by Wiley Periodicals LLC on behalf of American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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ZHX2 mRNA and protein levels are significantly higher in patients with hepatocellular carcinoma (HCC) and associated with clinical pathological parameters. UALCAN was used to analyze data from the Cancer Genome Atlas (TCGA) and the Clinical Proteomic Tumor Consortium (CPTAC). (A) ZHX2 protein expression in CPTAC samples. (B) ZHX2 mRNA expression in TCGA Liver Hepatocellular Carcinoma (LIHC) samples. (C–E) ZHX2 mRNA expression in TCGA‐LIHC samples based on histological subtypes (C), individual cancer stages (D), and tumor grade (E). *p < 0.05, ***p < 0.001, and ****p < 0.0001. Abbreviations: FLC, fibrolamellar carcinoma; HCC‐CC, hepatocholangiocarcinoma.