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. 2020 Sep 1;2020(9):CD011216. doi: 10.1002/14651858.CD011216.pub2

Summary of findings 3. Acupuncture or acupressure plus analgesia versus analgesia for post‐caesarean pain.

Acupuncture plus analgesia versus analgesia for post‐caesarean pain
Patient or population: post‐caesarean pain
Settings: maternity unit
Intervention: acupuncture or acupressure plus analgesia
Comparison: analgesia
Outcomes Anticipated absolute effects* (95% CI) Relative effect
(95% CI) No of Participants
(studies) Certainty of the evidence
(GRADE) Comments
Risk with analgesia Risk with Acupuncture or acupressureplus analgesia
Pain
Follow‐up: 12 hours
  SMD 0.28 SD lower
(0.64 lower to 0.07 higher) 130
(2 RCTs) ⊕⊕⊝⊝
low1,2 Acupuncture plus analgesia may reduce pain slightly compared with analgesia (SMD between 0.20 and 0.39 indicates a small effect)
Pain
Follow‐up: 24 hours
  SMD 0.63 SD lower
(0.99 lower to 0.26 lower) 130
(2 RCTs) ⊕⊕⊝⊝
low1,3 Acupuncture plus analgesia may reduce pain compared with analgesia (SMD between 0.5 and 0.79 indicates a moderate effect)
Adverse effects (pruritus) Follow‐up: up to 24 hours Study population RR 0.50 
(0.08 to 3.29) 60
(1 RCT) ⊕⊝⊝⊝
very low4,5  
100 per 1,000 50 per 1,000
(8 to 329)
Vital signs Not reported
Rescue analgesic requirement (cumulative dose) assessed with: mg The mean rescue analgesic requirement (cumulative dose) in the control group was 15.28 mg MD was 5 mg lower
(7.67 lower to 2.34 lower) 60
(1 RCT) ⊕⊕⊝⊝
low3,4  
Pain at six weeks after discharge Not reported
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).
CI: confidence interval; MD: mean difference; RCT: randomised controlled trial; RR: risk ratio; SD: standard deviation; SMD: standardised mean difference.
GRADE Working Group grades of evidence
High certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate; the true effect is likely to be substantially different from the estimate of effect.

1 Downgraded one level due to high risk of performance bias and unclear risk of selection and detection bias

2 Downgraded one level due to imprecision: 95% CI spans possible benefit and possible harm

3 Downgraded one level for imprecision: few participants

4 Downgraded one level due to high risk of performance bias and unclear risk of selection bias

5 Downgraded one level due to imprecision: few participants and 95% CI spans possible benefit and possible harm