Table 1.
Pathology (CERAD) | Negative | Negative | Positive | Positive |
Clinical dementia Dx | No | Yes | No | Yes |
N | 166 | 40 | 212 | 227 |
Age at death (SD) | 88.1 (6.58) | 91.8 (5.97) | 90.4 (6.19) | 91.5 (5.62) |
Female sex (%) | 110 (66.3%) | 25 (62.5%) | 151 (71.2%) | 164 (72.2%) |
APOE ε4 +ve (%) | 16 (9.6%) | 7 (17.5%) | 50 (23.6%) | 88 (38.8%) |
Education years (SD) | 15.0 (2.74) | 14.4 (2.86) | 14.5 (2.91) | 14.5 (2.98) |
Presence of infarcts (%) | 46 (27.7%) | 21 (52.5%) | 79 (37.3%) | 97 (42.7%) |
Presence of Lewy bodies (%) | 28 (16.9%) | 15 (37.5%) | 36 (17.0%) | 72 (31.7%) |
Aβ plaques: mm2 (SD) | 0.87 (1.59) | 0.59 (1.62) | 6.62 (4.12) | 7.04 (3.92) |
NFT: mm2 (SD) | 2.77 (2.68) | 3.71 (3.04) | 6.34 (5.87) | 13.3 (11.5) |