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. Author manuscript; available in PMC: 2022 Nov 28.
Published in final edited form as: Clin Genitourin Cancer. 2022 Feb 1;20(3):260–269. doi: 10.1016/j.clgc.2022.01.017

Figure 4.

Figure 4.

Endoscopic and histologic findings of ICI colitis. A-D: Representative endoscopic images. (A) normal gross appearance; (B) focal erythema (red arrow); (C) focal ulceration; (D) diffuse inflammation. E-G: Representative histologic findings. (E) Active inflammation characterized by cryptitis and crypt abscess, magnification 100x; (F) Expansion of chronic inflammation in lamina propria, magnification 100x; (G) Intraepithelial lymphocytosis and increased crypt epithelial apoptosis (red arrows), magnification 200x.