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. 2022 Nov 14;12:1019555. doi: 10.3389/fonc.2022.1019555

Table 5.

Impact of surgical margin status on five-year disease-specific and overall survival rates in the internal grouping (pathological stage and treatment modality) of Hospital 1 and Hospital 2.

Characteristic (n, %) Five-year disease-specific survival(margin ≥5 mm vs. <5 mm) p Five-year overall survival(margin ≥5 mm vs. <5 mm) p
Hospital 1 (n = 2009) 82% / 74% <0.0001 75% / 64% <0.0001
Pathological stage
 I-II (755, 37.6) 92% / 92% 0.9690 87% / 86% 0.8202
 III-IV (1254, 62.4) 74% / 67% 0.0030 66% / 55% 0.0013
Treatment modality
 Surgery (987, 49.1) 88% / 86% 0.3469 81% / 77% 0.2758
 Surgery plus adjuvant therapy (1022, 50.9) 74% / 68% 0.0278 66% / 58% 0.0229
Hospital 2 (n = 1019) 80% / 70% 0.0006 75% / 64% 0.0010
Pathological stage
 I-II (468, 45.9) 90% / 87% 0.2411 88% / 82% 0.1856
 III-IV (551, 54.1) 68% / 58% 0.0161 60% / 50% 0.0327
Treatment modality
 Surgery (553, 54.3) 88% / 79% 0.0409 83% / 73% 0.0486
 Surgery plus adjuvant therapy (466, 45.7) 70% / 61% 0.0089 65% / 54% 0.0091