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. 2022 Nov 14;9:943681. doi: 10.3389/fmed.2022.943681

Figure 4.

Figure 4

(A) 42 related intersections of drug (CSTRG) targets and influenza-related targets. (B) Protein-protein interaction (PPI) networks of CSTRG components with anti-influenza activity. The nodes represent related genes, and the strength of the data is supported when the circle is larger and the color is darker. (C) The functional enrichment analysis of CSTRG anti-influenza therapeutic targets was among the top 10 terms with the most significant enrichment in KEGG. (D) The five most significantly enriched BP, CC, and MF terms. (E) CSTRG component-target-disease network. The network was constructed to reveal interactions between active compounds and potential targets of CSTRG. Red triangular nodes represent the disease, cyan triangular nodes represent genes, blue round nodes represent Chinese medicines, and purple circular nodes represent active ingredients. The size of each target is positively related to its degree in the network.