Table 2.
Fisher's exact test results between immunohistochemistry status and response.
| Molecular biomarker | Responder | Non-responder | p value | |
|---|---|---|---|---|
| CD8 | Positive | 22 | 11 | 0.037 |
| Negative | 10 | 17 | ||
| CD4 | Positive | 5 | 14 | 0.006 |
| Negative | 27 | 14 | ||
| FoxP3 | Positive | 8 | 8 | 0.778 |
| Negative | 24 | 20 | ||
| CD3 | Positive | 12 | 12 | 0.793 |
| Negative | 20 | 16 | ||
| PD-L1 | Positive | 15 | 9 | 0.297 |
| Negative | 17 | 19 | ||
| CD68 | Positive | 14 | 3 | 0.009 |
| Negative | 18 | 25 | ||
| CD163 | Positive | 13 | 15 | 0.437 |
| Negative | 19 | 13 | ||
| CD57 | Positive | 8 | 8 | 0.778 |
| Negative | 24 | 20 | ||
| BCL-2 | Positive | 19 | 18 | 0.793 |
| Negative | 13 | 10 | ||
| XIAP | Positive | 15 | 12 | 0.799 |
| Negative | 17 | 16 | ||
| CD20 | Positive | 10 | 10 | 0.787 |
| Negative | 22 | 18 | ||
| TLS | Positive | 12 | 9 | 0.788 |
| Negative | 20 | 19 | ||
CD cluster of differentiation, FoxP3 forkhead box P3, PD-L1 programmed death-ligand 1, BCL2 B-cell/CLL lymphoma 2, XIAP X linked inhibitor of apoptosis protein, TLS tertiary lymphoid structures.
Responders: patients with CR, PR, or SD ≥ 10 months, non-responders: patients with PD or SD < 10 months.