FIGURE 1.

FXR is downregulated in colon cancer tissue and cells. (A) FXR expression data in colon cancer were downloaded from TCGA database. The level of FXR in colon cancer and adjacent tissue. (B) qRT‐PCR detected the level of FXR in four strains of colon cancer cell lines (HCT116, SW620, HT‐29, SW480) and one human normal colon cell line CCD‐18Co. (C) Western blot determined the protein expression of FXR in four strains of cancer cell lines (HCT116, SW620, HT‐29, SW480) and one human normal colon cell line CCD‐18Co, where β‐actin was the internal reference. (D) Quantification of Western blot band intensity from (C). * p < 0.05