Table.

Laboratory Investigations of the Patient

Laboratory investigations	Results at the time of the initial presentation of adrenal mass	Results at the time of diagnosis of hepatic metastases	Reference range
Serum potassium	2.3 mmol/L	2.3 mmol/L	3.5-5.1 mmol/L
Thyroid-stimulating hormone	0.45 mcIU/mL	0.397 mcIU/mL	0.4-4.3 mcIU/mL
Free thyroxine	1.29 ng/dL	0.8 ng/dL	0.6-1.6 ng/dL
Hemoglobin A1C	6.2% (44 mmol/mol)	8.5% (69 mmol/mol)	4.0%-6.0% (20-42 mmol/mol)
24-hour urine cortisol	285 mcg	3700.2 mcg	<45 ug/d
Salivary cortisol	0.383 mcg/dL	0.974 mcg/dL	<0.181 ug/dL
8 am serum cortisol after 1 mg of dexamethasone administered overnight	16.9 mcg/dL	37.8 mcg/dL	<1.8 mcg/dL; excludes Cushing syndrome
8 am serum cortisol after 8 mg of dexamethasone administered overnight	…	41.6 mcg/dL	<1.8 mcg/dL; excludes Cushing syndrome
Adrenocorticotropic hormone	<5	27 ng/mL in LDDST and 19 ng/mL in HDDST	<46 pg/mL
Dehydroepiandrosterone sulfate	51 mcg/dL	29 mcg/dL	Female premenopausal, 35-430 mcg/dL Postmenopausal, 10-240 mcg/dL
Estradiol	…	<20 ng/mL	Midfollicular, 27-123 pg/mL Periovulatory, 96-436 pg/mL Midluteal, 49-294 pg/mL Postmenopausal, 0-40 pg/mL
Androstenedione	4.3	0.348 ng/mL	0.26-2.14 ng/mL
Total testosterone	8.2 ng/dL	2 ng/dL	Premenopausal, 9-55 ng/dL Postmenopausal, 5-32 ng/dL
17-hydroxyprogesterone	…	98.6 ng/dL	<206 ng/dL
11-deoxy cortisol	…	725 ng/dL	<32 ng/dL
Chromogranin A	…	130 ng/mL	<160 ng/mL

Abbreviations: HDDST: high-dose 8 mg dexamethasone suppression test; LDDST: low-dose 1 mg dexamethasone suppression test.