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. 2020 Jun 27;74(Suppl 2):1949–1954. doi: 10.1007/s12070-020-01921-x

Table 1.

Univariate analysis

Variable No. of patients(n = 149)(%) No. of contralateral nodal recurrence(n = 13)(%) p value
Sex 0.549
 Male 102(68.5) 8(61.5)
 Female 47(31.5) 5(38.5)
Age(median = 51 years) 0.294
 Less than median 71(47.6) 8(61.5)
 More than median 78(52.4) 5(38.5)
Staging
Pathological T stage  < 0.001
 T1,T2 95(63.8) 2(15.4)
 T3,T4 49(32.9) 9(69.2)
 Complete NACT tumor response 5(3.3) 2(15.4)
Pathological N stage  < 0.001
 N0 83(55.7) 2(15.4)
 N1 16(10.7) 0(0)
 N2 29(19.5) 3(23.1)
 N3 21(14.1) 8(61.5)
 Composite stage 0.011
 Early stage (1/II) 63(42.3) 1(7.7)
 Advanced stage(III/IV) 82(55.0) 10(76.9)
 Complete NACT tumor response 5(3.3) 2(15.4)
Pathology
Tumor grade 0.093
Not ascertained 5(3.3) 2(15.4)
Well 20(13.4) 1(7.7)
Moderate/poor 124(83.2) 10(76.9)
Perineural invasion 0.071
Present 79(53) 10(76.9)
Absent 70(47) 3(23.1)
Lymphovascular emboli 0.221
Present 52(34.9) 7(53.8)
Absent 97(65.1) 6(46.2)
Tumor depth 0.012
0.1–0.5 cm 53(35.6) 1(7.7)
0.6–1.0 cm 48(32.2) 3(23.1)
More than 1 cm 48(32.2) 9(69.2)
Primary resection margin in frozen 0.179
Clear(> 0.5 cm) 72(48.3) 5(38.5)
Close(0.2 to 0.5 cm) 70(46.9) 6(46.2)
Involved(< 0.1 cm) 7(4.7) 2(15.4)
I/L Node ratio 0.002
 < 0.09 114(76.5) 5(38..5)
 > 0.09 35(23.5) 8(61.5)
Extracapsular spread in I/L node  < 0.001
Present 25(16.8) 9(69.2)
Absent 124(83.2) 4(30.8)
Clinical/surgical
I/L clinical neck node 0.081
Involved 57(38.3) 8(61.5)
Not involved 92(61.7) 5(38.5)
C/L clinical neck node  < 0.001
Involved 8(5.4) 7(53.8)
Not involved 141(94.6) 6(46.2)
Floor of mouth 0.001
Involved 39(26.2) 9(69.2)
Not involved 110(73.8) 4(30.8)
Lesion crossing midline  < 0.001
Present 33(24.1) 9(69.2)
Absent 116(75.9) 4(30.8)
Base of tongue involvement 0.054
Involved 18(12.1) 4(30.8)
Not involved 131(87.9) 9(69.2)
Reconstructions 0.001
Primary closure 85(57) 3(23)
Pedicled flap 14(9.4) 5(38.5)
Local/Free flap 50(33.6) 5(38.5)
Therapy
NACT 0.103
Given 22(14.8) 4(30.8)
Not given 127(85.2) 9(69.2)
Radiotherapy 0.185
Given 110(73.8) 12(92.3)
Not given 39(26.2) 1(7.7)