Table 3.

Results of logistic regression analyses for the impact of total fiber loss on general performance status (normal ECOG=0 vs. impaired ECOG ≥ 1).

Imaging finding#	Total fiber loss median (range)	p-value univariate	p-value multivariate
Resection cavity	7506 (0 - 171033)	0.906	0.692
Increased FET uptake	3977 (0 - 204533)	0.054	0.462
Contrast enhancement	1774 (0 - 102088)	0.006**	0.040*
T2/FLAIR hyperintensities	20265 (0 - 168450)	0.013*	0.310

FET, O-(2-[¹⁸F]fluoroethyl)-L-tyrosine; T2/FLAIR, T2-weighted fluid-attenuated inversion recovery; *p<0.05; **p<0.01; ^#including patients not affected by respective lesion type (lesion-specific volume/total fiber loss set to zero).