Table 2.
Correlation between gene mutation and overall survival.
| Gene | Median survival (months) | Log-rank test | ||
|---|---|---|---|---|
| Mutation | Wild type | HR (95% CI) | p-value | |
| APC | 75.8 (n = 1,238) | 56.9 (n = 415) | 0.65 (0.51–0.83) | <0.001 |
| KRAS | 64.7 (n = 720) | 87.9 (n = 933) | 1.30 (1.07–1.58) | 0.008 |
| PIK3CA | 75.8 (n = 374) | 70.7 (n = 1279) | 1.00 (0.78–1.27) | 0.985 |
| TP53 | 72.5 (n = 1,130) | 66.9 (n = 523) | 1.02 (0.82–1.27) | 0.850 |
APC, adenomatous polyposis coli; KRAS, Kirsten rat sarcoma viral oncogene homolog; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; TP53, tumor protein p53; HR, hazard ratio.