Table 2.

Acute toxicities

Toxicity	Arm 1 (cisplatin100 mg/m2)	Arm 2 (cisplatin 40 mg/m2)	P value
Nausea grade 2	20(49%)	17(39%)	0.458
Vomiting grade 2	20(49%)	11(25%)	0.150
Acute skin reaction grade 2	19(46%)	12(27%)	0.679
Dysphagia grade 3	23(56%)	19(43%)	0.449
Mucositis grade ¾	28(68%)	25(57%)	0.714
Anaemia grade 2	26(63%)	25(57%)	0.824
Leukopenia	38(93%)	28(64%)	0.003 (significant)
Thrombocytopenia	17(41%)	10(23%)	0.04 (significant)
Ototoxicity	8(19.5%)	7(15.9%)	0.77
Acute renal toxicity	34(83%)	16(36%)	0.004 (significant)