FIGURE 1.
Domain organizations of eukaryotic PUFA synthases. On the left are the native sources and main products of PUFA synthases. Different domains are indicated by colors. ACP, acyl carrier protein domain; MAT, malonyl-CoA: ACP transacylase domain; KS, ketoacyl-ACP synthase domain; CLF, chain length factor domain; KR, ketoacyl-ACP reductase domain; DHPKS, PKS-like dehydratase domain; DHFabA, FabA-like dehydratase domain; ER, enoyl-ACP reductase domain; AT, acyltransferase domain. The subscripts A, B and C indicate that the corresponding domain is located in subunits A, B and C, respectively.