Fig. 3. Hepatic protein expression and mRNA level of COX-2 after the oral administration of L-methionine for 14 days. (A) Hepatic protein expression of COX-2. (B) Hepatic mRNA level of COX-2. The values are expressed as the means ± SEM (n = 6).

COX-2, cyclooxygenase-2; C, control; M50, basal diet and administered L-methionine orally at 215.0 mg/kg bw; M62.5, basal diet and administered L-methionine orally at 268.8 mg/kg bw; M75, basal diet and administered L-methionine orally at 322.5 mg/kg bw; M100, basal diet and administered L-methionine orally at 430.0 mg/kg bw.

^*P < 0.05, in comparison with C.