Fig. 2. Effect of various protein sources on the colitis activity. Female Balb/c mice in 20CD, 40CD, 40WD, 40SD, 40WMD, 40RMD group were administered 3% DSS in drinking water for 6 days. Control group received tap water. (A) Disease activity index of mice was monitored during DSS treatment. (B) The survival rate of mice was monitored during and after 2 days of the DSS treatment. (C) The weight and length of entire large intestine was measured and the weight/length ratio was calculated. (D) MPO activities were assayed in colorectal tissue. (E) Colorectal tissue sections were stained with hematoxylin and eosin. Representative histological pictures of mice are shown at 40× magnification. Means with different letters are significantly different at P < 0.05 by Duncan’s multiple range test.

20C, 20% casein; 20CD, 20% casein-DSS; 40CD, 40% casein-DSS; 40WD, 40% whey protein-DSS; 40SD, 40% soy protein-DSS; 40WMD, 40% white meat-DSS; 40RMD, 40% red meat-DSS; DSS, dextran sulfate sodium; MPO, myeloperoxidase.