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IFN-γ induction by B. abortus, bDNA, and LPS. BALB/c spleen cells were cultured with the indicated stimuli; supernatants were harvested at 24, 48, and 72 h, and supernatants were assayed for IFN-γ by ELISA. LPS was derived from either E. coli (LPS-EC) or B. abortus (LPS-BA). Controls include cells stimulated with eukaryotic herring testis DNA (DNA-HT) and untreated cells.
