Precision and accuracy of the proposed β-CD-modified AuNPs/EME method for quantification of methadone in plasma samples.
| Added concentration (ng mL−1) | Intra-day assay (n = 5)a | Inter-day assay (n = 5) | ||
|---|---|---|---|---|
| RSDb (%) | REc (%) | RSD (%) | RE (%) | |
| 5 | 7.81 | 8.83 | 8.71 | 7.51 |
| 15 | 5.01 | −3.42 | 6.11 | −5.73 |
| 100 | 1.77 | 8.04 | 2.41 | 8.31 |
| 500 | 6.01 | 8.79 | 11.21 | −2.72 |
Number of replicates.
Relative standard deviation.
Relative error.