Table 2.

Hazard ratios for the combined associations of DM and CI with all-cause and cause-specific mortality.

	Normal cognition and non-DM	Normal cognition and DM	CI and non-DM	CI and DM
Participants, no.	2,836	900	587	176
All-cause mortality
Death, No.	346	156	108	57
Model 1 a	1 (ref)	1.34 (1.11,1.62)*	2.09 (1.68,2.60)*	3.58 (2.71,4.75)*
Model 2 b	1 (ref)	1.39 (1.15,1.68)*	1.63 (1.30,2.03)*	3.21 (2.42,4.26)*
Model 3 c	1 (ref)	1.42 (1.17,1.72)*	1.37 (1.08,1.72)**	3.12 (2.34,4.16)*
Model 4 d	1 (ref)	1.42 (1.16,1.72)*	1.39 (1.09,1.74)**	3.08 (2.30,4.11)*
CVD mortality
Death, no.	144	63	52	33
Model 1 a	1 (ref)	1.30 (0.97,1.75)	2.52 (1.83,3.47)	5.13 (3.51,7.50)*
Model 2 b	1 (ref)	1.35 (1.01,1.82)**	1.79 (1.29,2.49)*	4.45 (3.05,6.51)*
Model 3 c	1 (ref)	1.38 (1.02,1.87)**	1.48 (1.05,2.08)***	4.07 (2.75,6.02)*
Model 4 d	1 (ref)	1.32 (0.97,1.79)	1.53 (1.09,2.15)***	3.85 (2.60,5.71)*
Cancer mortality
Death, no.	118	53	35	9
Model 1 a	1 (ref)	1.35 (0.98,1.87)	1.88 (1.29,2.75)**	1.59 (0.81,3.13)
Model 2 b	1 (ref)	1.39 (1.01,1.93)**	1.69 (1.15,2.49)**	1.54 (0.78,3.04)
Model 3 c	1 (ref)	1.46 (1.05,2.03)**	1.47 (1.00,2.20)***	1.54 (0.78,3.06)
Model 4 d	1 (ref)	1.47 (1.05,2.06)**	1.49 (1.00,2.22)***	1.56 (0.78,3.11)

CI, cognitive impairment; DM, diabetes mellitus; CVD, cardiovascular disease; HRs, hazard ratios.

^aAn unadjusted model.

^bAdjusted for age and gender.

^cFurther adjusted for residence, education, marriage, smoking status, alcohol drinking, exercise, and BMI.

^dFurther adjusted for WC, chronic diseases (hypertension, dyslipidemia, coronary disease, COPD, and tumor), TC, TG, and uric acid.

*p<0.001;**p<0.01;***p ≤ 0.05.