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. 2022 Nov 14;13:1033327. doi: 10.3389/fneur.2022.1033327

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Copyright © 2022 Dong, Wang, Xu, Hu, Yu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Timeline of the case and ELISA results of antibodies against ganglioside complexes. (A) The patient started inhaling N₂O occasionally 2 years ago, felt numbness and weakness 2 months ago, significantly improved after receiving the treatment of IVIG, and almost recovered 6 months after the admission. (B) ELISA tests indicated the anti-GM1 IgM antibodies were positive in both CSF and serum while anti-GM1 IgG antibodies were negative. IVIG, intravenous immunoglobulin; CSF, cerebrospinal fluid.