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. 2022 Dec;12(12):5383–5393. doi: 10.21037/qims-22-263

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2022 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A non-responder of a 54-year-old man with histologically proven left maxillary cancer. (A-D) Before induction chemotherapy. (E-H) After one cycle of induction chemotherapy. (A) An axial T2-weighted image showing left maxillary cancer with intermediate signal intensity. (B) The corresponding DWI image with the identical lesion for the reconstruction of ADC measurements. (C) The corresponding ADC map with the identical lesion. (D) A whole-lesion histogram analysis based on the ADC map before induction chemotherapy. (E) An axial T2-weighted image showing stable size of left buccal cancer with intermediate signal intensity. (F) The corresponding DWI image with the identical lesion for the reconstruction of ADC measurements. (G) The corresponding ADC map with the identical lesion. (H) A whole-lesion histogram analysis based on the ADC map after one cycle of induction chemotherapy. DWI, diffusion-weighted magnetic resonance imaging; ADC, apparent diffusion coefficient.