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. 2022 Aug 2;14(6):1311–1331. doi: 10.1016/j.jcmgh.2022.07.011

Figure 1.

Figure 1

Decreased LW/BW and survival rate in mTORC2 deficient mice after PH. (A) Representative western blot analysis of rictor proteins in control mice liver samples after PH. Protein quantification was normalized to β-tubulin (n = 3 per group). (B) Representative Western blot analysis of Rictor proteins in liver samples isolated from control (Ctrl) and R-LKO mice. Quantifications were normalized to β-tubulin (n = 4 mice for each time point). (C) Survival curves of Ctrl (n = 20 mice) and R-LKO (n = 22 mice) mice after 2/3 PH. (D) LW/BW of Ctrl (green) and R-LKO mice at 24 and 48 hours after PH (4–6 mice per group). (E) Analysis of serum glucose in Ctrl and R-LKO mice at the indicated time points after 2/3 PH (n = 4 mice for each time point). Immunohistochemistry slices were scanned and captured by Pannoramic MIDI (3D HISTECH, Ltd). Error bars represent the means ± SD. ∗P < .05, ∗∗∗P < .001.