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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Prev Vet Med. 2022 Sep 23;208:105767. doi: 10.1016/j.prevetmed.2022.105767

Table 5.

Association between resistance to ceftiofur, enrofloxacin, or trimethoprim-sulfamethoxazole and other antimicrobial compounds among Escherichia coli urinary isolates using multivariable logistic regression models.

Model 1a Model 2a
adj. OR 95% CI P-value adj. P-value § adj. OR 95% CI P-value adj. P-value §
Resistance to ceftiofur (N = 3562 isolates)
Resistance to ampicillin 115.4 (24.7–2059) < 0.001 < 0.001 115.4 (24.7–2059) < 0.001 < 0.001
Resistance to amoxicillin-clavulanate 20.3 (13.8–30.5) < 0.001 < 0.001 20.3 (13.8–30.5) < 0.001 < 0.001
Resistance to tetracycline 1.32 (0.90–1.93) 0.149 0.155 1.32 (0.90–1.93) 0.149 0.155
Resistance to enrofloxacin 4.84 (3.32–7.14) < 0.001 < 0.001 4.84 (3.32–7.14) < 0.001 < 0.001
Resistance to trimethoprim-sulfamethoxazole 1.55 (1.03–2.35) 0.036 0.040 1.55 (1.03–2.35) 0.036 0.040
Resistance to enrofloxacin (N = 3562 isolates)
Resistance to ampicillin 5.68 (3.96–8.16) < 0.001 < 0.001 5.68 (3.96–8.16) < 0.001 < 0.001
Resistance to amoxicillin-clavulanate 0.60 (0.40–0.88) 0.011 0.013 0.60 (0.40–0.88) 0.011 0.013
Resistance to ceftiofur 4.78 (3.26–7.10) < 0.001 < 0.001 4.78 (3.26–7.10) < 0.001 < 0.001
Resistance to tetracycline 3.36 (2.50–4.50) < 0.001 < 0.001 3.36 (2.50–4.50) < 0.001 < 0.001
Resistance to trimethoprim-sulfamethoxazole 5.20 (3.81–7.09) < 0.001 < 0.001 5.20 (3.81–7.09) < 0.001 < 0.001
Resistance to trimethoprim-sulfamethoxazole (N = 3562 isolates)
Resistance to ampicillin 6.83 (4.71–9.98) < 0.001 < 0.001 6.91 (4.76–10.1) < 0.001 < 0.001
Resistance to amoxicillin-clavulanate 0.54 (0.36–0.80) 0.003 0.004 0.61 (0.43–0.84) 0.003 0.004
Resistance to ceftiofur 1.23 (0.81–1.86) 0.326 0.326
Resistance to tetracycline 7.85 (5.85–10.6) < 0.001 < 0.001 7.93 (5.92–10.7) < 0.001 < 0.001
Resistance to enrofloxacin 5.48 (4.01–7.48) < 0.001 < 0.001 5.74 (4.27–7.73) < 0.001 < 0.001
a

In model 1, selected antimicrobials regularly tested on urinary Escherichia coli isolates were entered in the model as explanatory variables.

ii

In model 2, a backward logistic regression model was created including only complete cases.

§

P-values were adjusted according to (Benjamini and Hochberg, 1995).