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. 2022 Nov 25;12(11):e064673. doi: 10.1136/bmjopen-2022-064673

Table 4.

Treatment effects of included studies

No Author(s) Year Programme and benefits
(adjusted for inflation, showing 2022 value)
Outcome description Treatment effect Statistical information Data source
Individual randomised controlled trials
1 Grépin et al31 2019 M-Kadi (Kenya)
US$29.5 per pregnancy
Four or more ANC visits 0.045 RC
(6.9% increase)
Control: 0.65
95% CI: NA
SE: 0.068
P>0.1
Registers and survey (conducted by programme)
Cluster randomised controlled trials
2 Barber and Gertler27 2010 Oportunidades (Mexico)
US$172.5 per pregnancy
Any prenatal care 0.034 RC
(3.6% increase)
Control: 0.943
95% CI: NA
SE: 0.236
Survey
(ENCEL survey, socioeconomic survey and fertility survey)
Obtained five prenatal care visits 0.015 RC
(2% increase)
Control: 0.742
95% CI: NA
SE: 0.130
Number of prenatal visits −0.0348 RC
(0.5% decrease)
Control: 6.40
95% CI: NA
SE: 0.037
3 Kandpal et al36 2016 Pantawid Pamilya (Philippines)
US$57.5–US$167.5 per pregnancy
Four or more ANC visits 7.648 RC
(13.9% increase)
Control: 54.911
95% CI −3.148 to 18.443
P>0.1
Survey
(specific impact evaluation, Family Income and Expenditure Survey and NDHS)
Number of times ANC was received 0.596 RC
(14.4% increase)
Control: 4.147
95% CI −0.088 to 1.280
P=0.09
4 Okeke and Abubakar29 2020 CCT programme (Nigeria)
US$15 per pregnancy
Number of prenatal visits attended 0.471 RC
(19.8% increase)
Control: 2.378
95% CI: NA
SE: 0.0655
P<0.01
Survey
(conducted by programme)
5 Triyana26 2016 Program Keluarga Harapan (Indonesia)
US$52.5–US$191.5 per pregnancy
Prenatal visits 0.084 RC
(1.2% increase)
Control: 7.00
95% CI: NA
SE: 0.317
P>0.1
Survey
(conducted by National Planning Agency and World Bank)
6 Vanhuyse et al30 2022 Afya Credits Incentive (Kenya)
US$31.5 per pregnancy
Nurses receive US$5 for each woman enrolled in the CCT programme.
Antenatal care appointments attended 1.90 OR
(odds of ANC being 1.9 times higher than control group)
Control: NA
95% CI 1.36 to 2.66
P<0.001
Survey
(conducted by programme)
Electronic card reading system
Controlled before-after studies (all applied difference-in-differences methodology)
7 Kusuma et al37 2016 Program Keluarga Harapan (Indonesia)
US$52.5–US$191.5 per pregnancy
Four or more prenatal visits 0.039 RC
(5.7% increase)
Control: 0.68
95% CI: NA
SE: 0.023
P<0.1
Survey (conducted by National Planning Agency and World Bank)
8 de Brauw and Peterman35 2020 Comunidades Solidarias Rurales (El Salvador)
US$145.5–US$194 per pregnancy
Five or more prenatal visits −0.102 RC
(13.7% decrease)
Control: 0.744
95% CI: NA
SE: 0.073
P=0.206
Survey
(conducted by IFPRI and FUSADES)
9 Díaz and Saldarriaga41 2019 JUNTOS (Peru)
US$343.5 per pregnancy
Number of prenatal appointments 0.328 RC
(4.7% increase)
Control: 7.009
95% CI: NA
SE: 0.148
P<0.05
Survey
(Peruvian DHS)
One or more ANC visits 0.028 RC
(2.9% increase)
Control: 0.955
95% CI: NA
SE: 0.011
P<0.05
Four or more ANC visits 0.048 RC
(5.5% increase)
Control: 0.876
95% CI: NA
SE: 0.017
P<0.01
10 Edmond et al34 2019 CCT programme (Afghanistan)
US$16.5 per pregnancy
Community health workers receive US$5.5 for each facility-based delivery.
One or more ANC visits 45.0% AMD
(45.0% higher than control group)
Control: NA
95% CI 0.18 to 0.72
P=0.004
Survey
HMIS
11 Chakrabarti et al39 2021 Mamata Scheme (India)
US$70 per pregnancy
Community health workers receive US$2.5 per programme beneficiary.
Four or more ANC visits 1.51 OR
(odds of ANC being 1.51 times higher than control group)
Control: NA
95% CI 1.15 to 1.99
Survey
(NFHS second, third and fourth waves)
12 Powell-Jackson et al38 2015 Safe Motherhood Programme (India)
US$8.5–US$20.5 per pregnancy
Community health workers receive US$3 for each facility-based delivery.
Three or more ANC visits 0.010 RC
(2.2% increase)
Control: 0.45
95% CI: NA
SE: 0.0073
P>0.1
Survey
(DLHS-II and DLHS-III)
13 Aizawa40 2020 Safe Motherhood Programme (India)
US$8.5–US$20.5 per pregnancy
Community health workers receive US$3 for each facility-based delivery.
Three or more ANC visits 0.0962 RC
(22.9% increase)
Control: 0.42
95% CI: NA
SE: 0.0113
P<0.01
Survey
(NFHS third and fourth waves)
14 Joshi and Sivaram32 2014 Safe Motherhood Programme (India)
US$8.5–US$20.5 per pregnancy
Community health workers receive US$3 for each facility-based delivery.
Three or more ANC visits −0.004 RC
(1.3% decrease)
Control: 0.298
95% CI: NA
SE: 0.010
P>0.1
Survey
(DLHS-II and DLHS-III)
15 Lim et al42 2010 Safe Motherhood Programme (India)
US$8.5–US$20.5 per pregnancy
Community health workers receive US$3 for each facility-based delivery.
Three or more ANC visits 10.7% (increase among treatment group, using ‘exact matching’) Control: NA
95% CI 0.091 to 0.123
Survey
(DLHS-II and DLHS-III)
11.1% (increase among treatment group, using ‘with vs without’) Control: NA
95% CI 0.101 to 0.121
10.9% (increase among treatment group, using ‘difference-in-differences’) Control: NA
95% CI 0.046 to 0.172
16 Debnath44 2021 Safe Motherhood Programme (India)
US$8.5–US$20.5 per pregnancy
Community health workers receive US$3 for each facility-based delivery.
Any prenatal care 0.022 RC
(2.4% increase)
Control: 0.908
95% CI 0.013 to 0.032
SE: 0.005
P<0.01
Survey
(DLHS-II and DLHS-III)
Interrupted time series analysis
17 Powell-Jackson et al43 2009 Safe Delivery Incentive Programme (Nepal)
US$21 per pregnancy
Healthcare provider receives US$6.5 per assisted delivery.
Number of ANC visits 0.031 RC
(2.5% increase)
Using quartic time function
Control: 1.235
T-statistic: 0.38
95% CI: NA
Community surveillance system data set
−0.046 RC
(3.7% decrease)
Using quadratic time function
Control: 1.235
T-statistic: −0.75
95% CI: NA
18 Okoli et al33 2014 SURE-P/MCH (Nigeria)
US$35.5 per pregnancy
Four or more ANC visits 15.1152 RC
(increase of 15.1 visits per 100 000 population)
Control: NA
T-statistic: 4.13
P=0.001
95% CI 7.38 to 22.85
Programme monitoring data
(from facility logbooks)
Number of first ANC visits −8.3150 RC
(decrease of 8.3 visits per 100 000 population)
Control: NA
T-statistic: −1.29
P=0.213
95% CI −21.87 to 5.24

Treatment effects include regression coefficients (RC), odds ratios (OR), adjusted means difference (AMD) or other types described in full. Financial benefits are maximum amounts and can vary among beneficiaries depending on compliance with conditions. Amounts per pregnancy presented in 2022 values using US Inflation Calculator.24

ANC, antenatal care; CCT, conditional cash transfer; CI, confidence interval; DHS, Demographic and Health Survey; DLHS, District Level Health Survey; ENCEL, Encuesta Evaluation de los Hogares; FUSADES, Fundación Salvadoreña para El Desarrollo Económico y Social; HMIS, Health Management Information System; IFPRI, International Food Policy Research Institute; NA, not available; NDHS, National Demographic and Health Survey; NFHS, National Family Health Survey; SE, standard error; SURE-P/MCH, Subsidy Reinvestment and Empowerment Programme/Maternal and Child Health.