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. 2022 Nov 28;14(11):e31960. doi: 10.7759/cureus.31960

Table 12. Summary of articles that investigate in-hospital mortality and complications with statistical relationships to various risk factors for SCI patients.

ASIA: American Spinal Cord Injury Association; GCS: Glasgow Coma Scale; ISS: Injury Severity Score; SCI: spinal cord injury; TBI: traumatic brain injury

Author, year, country Sample In-hospital mortality The primary cause of death Analysis technique: factors associated with in-hospital mortality
Shao et al. [9], 2011, China N=1163, cervical SCI 9.4% (n=109) Respiratory failure, 87.2% (n=95) Logistic regression: -age -ASIA A -time to surgery -malnutrition -tracheotomy
Selassie et al. [17], 2012, USA N=3389, all SCI 8.0% (n=272) - Cox proportional hazard regression model: -age -level of injury -2 or more comorbidities -concomitant injuries -pulmonary embolism
Durga et al. [33], 2010, India N=101, postoperative, cervical SCI 17.8% - Logistic regression: -ASIA -haemodynamic instability -pulmonary infection
Chhabra et al. [10], 2019, India N=758, all SCI 10% (n=79) Respiratory complications including pulmonary embolism and pneumonia (42%) Cox proportional hazard regression: -age -low tetraplegia -ventilator use -associated injuries -cardiovascular complication
Inglis et al. [19], 2020, Canada N=826, postoperative all SCI, age over 65 years 9.5% (n=78) - Logistical regression: -age -ASIA A -Charlson Comorbidity Index -ventilation dependence
Gong et al. [11], 2022, China N=3176, all SCI 0.7% (n=23) Respiratory complication, 73.9% (n=17) Logistic regression: -cervical level -abdominal visceral injury -ASIA classification -surgery
Blex et al. [32], 2022, Germany N=321, all SCI 6.2% (n=20) Multiorgan failure, 40.0% (n=8) Condition inference tree analysis: -age -Charlson Comorbidity Index -kidney or liver impairment
Shibahashi et al. [21], 2019, Japan N=8069, all SCI 5.6% - Logistic regression: -age -male -GCS -hypotension on arrival -bradycardia on arrival -severe head injury -ISS -ASIA classification
Varma et al. [18], 2010, USA N=1995, all SCI 12.6% (n=251)  - Logistic regression: -age -male -ISS >15 -TBI -1 or more comorbidities -ASIA classification
Jackson et al. [20], 2005, USA N=458, postoperative, cervical SCI 3.9% - -Age >65 years -ASIA A
Beck et al. [41], 2019, Australia N=706, all SCI 15% (n=104) - Χ2 test: -age