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. 2022 Nov 28;7:154. doi: 10.1038/s41541-022-00573-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Correlation matrix showing pairwise correlations of the mean gene log2-transformed fold changes between the different vaccines at time-points with peak transcriptional responses. Transcriptional responses peaked on day 7 for live-attenuated vaccines and Pneumovax, day 3 for H5N1 and day 1 for all other vaccines. Size and intensity of dots are proportional to the magnitude of correlation coefficient. b Pearson correlation of log2-transformed fold-changes of transcripts in subjects receiving rVSV-ZEBOV vs ARCT-21 at day 1 post-vaccination^26,27. r = correlation coefficient, p = significance of correlation.