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. 2022 Nov 15;30:569–584. doi: 10.1016/j.omtn.2022.11.010

Figure 3.

Figure 3

Effect of radiation and impact of pre-treatment with CDX-301 on upstream signaling molecules in the murine serum

Upstream regulators are activated and inhibited in (A) Rd7V, (B) Rd7D, (C) Rd14V, and (D) Rd14D groups compared with NRV control groups in the murine serum samples. The color scheme indicates the relative value of the differential expressions and the shapes indicate the type and function, as indicated in Figure S1. Solid arrows represent the genes that interact directly, and dashed arrows represent indirect interactions between genes.