Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Treatment-Related Adverse Events.
| Adverse events | All Grades, % | Grade 1, % | Grade 2, % | Grade 3, % | Grade 4, % |
|---|---|---|---|---|---|
| Leukopenia | 44 | 8 | 20 | 15 | 1 |
| Neutropenia | 47 | 12 | 15 | 17 | 4 |
| Anemia | 89 | 52 | 29 | 8 | 0 |
| Thrombocytopenia | 35 | 15 | 16 | 3 | 1 |
| Bilirubin | 18 | 7 | 6 | 4 | 0 |
| ALT | 36 | 25 | 5 | 6 | 0 |
| AST | 41 | 28 | 9 | 4 | 0 |
| Diarrhea | 8 | 6 | 2 | 0 | 0 |
| Fatigue | 26 | 15 | 9 | 2 | 0 |
| Vomiting | 27 | 19 | 8 | 0 | 0 |
| Peripheral neuropathy | 20 | 15 | 5 | 0 | 0 |
| Skin allergy | 7 | 7 | 0 | 0 | 0 |
Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase.
