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Generation of steroidogenic tissue-specific seipin KO mice. A: Bcsl2 (seipin) mRNA expression in tissues of control and seipin KO mice. mRNA was isolated from adrenal and other tissues (n = 4) and analyzed using TaqMan quantitative PCR as described in the Materials and methods section. Data are expressed as mean ± SEM. B: Immunohistochemical staining of seipin in adrenal, testis, and ovary of control and seipin KO mice (scale bar in each panel represents 100 μm).
