Table 2.
HPV found in penile cancer cases and controls, p-values calculated with Chi-squared tests and binary logistic regression with crude odds ratios and 95% confidence interval
| All penile cancer cases N = 135 (%) | All cases, 10 mm adjacent to tumor N = 132 (%) | Age-matched controls N = 105 (%) | P-value (Chi-2) | Crude OR b (95% CI) | |
|---|---|---|---|---|---|
| Any HPV type | 38.5 (52/135) | 30.3 (40/132) | 11.4 (12/105) | < 0.001 | 4.9 (2.4–9.7) |
| High risk HPV type | 35.6 (48/135) | 25.8 (34/132) | 4.8 (5/105) | < 0.001a | 16.8 (3.6–78.0) |
| Low risk HPV only | 3.0 (4/135) | 4.5 (6/132) | 6.7 (7/105) | < 0.001a | 0.06 (0.01–0.3) |
| HPV16 | 27.4 (37/135) | 17.4 (23/132) | 1.0 (1/105) | < 0.001a | 27.1 (3.2–229.1) |
| Multiple HPV types | 3.7 (5/135) | 5.3 (7/132) | 1.0 (1/105) | 1.0a | 1.2 (0.1–11.0) |
a Fisher exact test
b Crude odds ratios after binary logistic regression with all penile cancer cases and age-matched controls