Table 2.
Minimum bactericidal concentrations of manuka honey and azithromycin both alone and in combination against M. abscessus and subspecies (n = 4).
| M. abscessus isolate | Honey alone MBC (g/mL) | Honey combination MBC (g/mL) | Azithromycin alone MBC (µg/mL) | Azithromycin combination MBC (µg/mL) |
|---|---|---|---|---|
| MGO40 | ||||
| NCTC 13031 | 0.476 | 0.117 | >16 | 16 |
| subsp. abscessus | 0.476 | 0.117 | >16 | 4 |
| subsp. bolletii | 0.476 | 0.117 | >16 | 16 |
| subsp. massiliense | 0.476 | 0.037 | >16 | 0.5 |
| MGO55 | ||||
| NCTC 13031 | 0.476 | 0.117 | >16 | 16 |
| subsp. abscessus | 0.476 | 0.117 | >16 | 2 |
| subsp. bolletii | 0.476 | No interaction | >16 | No interaction |
| subsp. massiliense | 0.476 | 0.037 | >16 | 0.5 |
| MGO70 | ||||
| NCTC 13031 | 0.476 | 0.037 | >16 | 4 |
| subsp. abscessus | 0.476 | 0.037 | >16 | 1 |
| subsp. bolletii | 0.476 | No interaction | >16 | No interaction |
| subsp. massiliense | 0.476 | 0.037 | >16 | 1 |
| MGO83 | ||||
| NCTC 13031 | 0.476 | 0.037 | >16 | 1 |
| subsp. abscessus | 0.476 | 0.037 | >16 | 2 |
| subsp. bolletii | 0.476 | No interaction | >16 | No interaction |
| subsp. massiliense | 0.476 | 0.037 | >16 | 1 |