TABLE 4.
Relationship between geometric mean reciprocal Inaba vibriocidal titer on day 10 after immunization and titer immediately before challenge and protection against experimental challenge with V. cholerae O1 El Tor Inaba among all vaccinees, vaccinees of blood group O, and vaccinees of non-O blood groups
| Symptom group | All vaccinees
(n = 28)
|
Vaccinees of blood group O
(n = 15)
|
Vaccinees of non-O blood groups
(n = 13)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| n | Titer 10 days after immunization | Titer before challenge | n | Titer 10 days after immunization | Titer before challenge | n | Titer 10 days after immunization | Titer before challenge | |
| No diarrhea | 23 | 4,968 | 244 | 11 | 6,185 | 341 | 12 | 4,064 | 180 |
| Mild diarrhea | 4 | 1,810 | 95 | 3 | 1,280 | 101 | 1 | 5,120 | 80 |
| Moderate or severe diarrhea | 1 | 20,480 | 1,280 | 1 | 20,480 | 1,280 | 0 | ||