Fig. 5.

Determination of microhomology usage. For reads classified as deletions, sequence microhomologies may mediate the repair event. These microhomologies are detected by examining the sequence to the left of the deletion in the read, and the sequence inside the deletion on the right side, as shown here. The same process is repeated for the sequence to the right of the deletion in the read (not shown here). The microhomologies detected are then combined into a single sequence.