TABLE 4.
Previous clinical, bacteriological, and serological responses of healthy volunteers to various doses of V. cholerae O139 (AI1837)a
| No. of CFU in inoculum | No. of volunteers with cholera/total no. of volunteers (%) | Mean incubation time (h) | Mean diarrheal stool vol (kg) per ill volunteer (range) | No. of volunteers with indicated
condition/total no. of volunteers (%)
|
||
|---|---|---|---|---|---|---|
| Positive stool culture | Significant rise in serum antitoxin antibody | Significant rise in serum vibriocidal antibody | ||||
| 104 | 2/4 (50) | 48 | 1.9 (0.7–3) | 3/4 (75) | 3/4 (75) | 0/4 |
| 106 | 30/37 (82) | 31 | 3.95 (0.4–16.5) | 35/37 (95) | 23/24 (96) | 0/24 |