Table 2.
Scope of reaction with various substituted phenols (3b–p).
| |||
|
| |||
| Entry | Substrates | Products | Yield of 2 (%)a |
|
| |||
| 1 |
3b |
2b |
70 |
| 2 |
3c |
2c |
85 |
| 3b |
3d |
2d |
68 |
| 4b |
3e |
2e |
63 |
| 5 |
3f |
2f |
76 |
| 6 |
3g |
2g |
41 |
| 7c |
3h |
2h |
39 |
| 8c |
3i |
2i |
18 |
| 9 |
3j |
2j |
75 |
| 10c |
3k |
2k |
54 |
| 11 |
3l |
2l |
51 |
| 12d |
3m |
2m |
9 |
| 13e |
3n |
2n |
32 |
| 14f |
3o |
2o |
66 |
| 15b,g |
3p |
2p |
69 |
aIsolated yield; b3 (1.0 equiv) was used; cDME (0.5 M) was used; dreaction time was 6.5 h; eTHF was used instead of DME; f3 (1.2 equiv) was used; ghalothane (1.5 equiv) was used.