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Susceptibility activities of BBR and FLC alone and in combination against T. marneffei.
| Isolates | Alone MIC(μg/ml) | Combination MIC(μg/ml) | FICI | Mode of interaction | |||
|---|---|---|---|---|---|---|---|
| BBR | FLC | BBR | FLC | ||||
| WT | 32 | 2 | 8 | 0.5 | 0.5 | Synergism | |
| B4 | 32 | 256 | 8 | 8 | 0.28 | Synergism | |
FICI: fractional inhibitory concentration index; synergy, FICI ≤ 0.5; indifferent, FICI>0.5 and ≤ 4.0; antagonism, FICI>4.0.
