TABLE 2.
Multivariable analysis of factors associated with receiving post-operative radiotherapy after R0 resection in National Cancer Data Base from 2004 to 2014 for early-stage non-small cell lung cancer
| Characteristic | p value | OR | 95% CI |
|
|---|---|---|---|---|
| Upper | Lower | |||
|
| ||||
| Facility type | ||||
| Community cancer program (RL) | ||||
| Comprehensive community cancer program | <0.001 | 0.707 | 0.641 | 0.779 |
| Academic/research program | <0.001 | 0.566 | 0.508 | 0.630 |
| Integrated network cancer program | <0.001 | 0.609 | 0.523 | 0.710 |
| Other specified types of cancer programs | 0.399 | 0.755 | 0.392 | 1.452 |
| Facility location | ||||
| East North Central | <0.001 | 1.155 | 1.069 | 1.248 |
| West North Central | <0.001 | 0.663 | 0.580 | 0.759 |
| Mountain | 0.002 | 0.730 | 0.601 | 0.887 |
| Gender | ||||
| Male (RL) | ||||
| Female | <0.001 | 0.864 | 0.812 | 0.920 |
| Age (years) | ||||
| ≥65 | 0.540 | 1.021 | 0.955 | 1.092 |
| Race | ||||
| White (RL) | ||||
| Black | 0.019 | 1.141 | 1.022 | 1.274 |
| Other | 0.141 | 0.847 | 0.680 | 1.057 |
| Urban/rural | ||||
| Counties in metro areas of 1 million population or more | 0.007 | 0.817 | 0.706 | 0.945 |
| Counties in metro areas of 250,000 to 1 million population | 0.239 | 0.914 | 0.786 | 1.062 |
| Counties in metro areas of fewer than 250,000 population | 0.393 | 1.071 | 0.915 | 1.255 |
| Urban population of 20,000 or more, adjacent to a metro area | 0.479 | 1.068 | 0.890 | 1.281 |
| Urban population of 2500–19,999, adjacent to metro area | 0.001 | 1.316 | 1.111 | 1.557 |
| Patient distance from facility | ||||
| >20 miles | <0.001 | 0.762 | 0.698 | 0.832 |
| Comorbidity score | ||||
| Score = 0 | 0.017 | 0.927 | 0.870 | 0.986 |
| Tumor size | ||||
| <3 cm (RL) | ||||
| 3–7 cm | <0.001 | 1.336 | 1.245 | 1.434 |
| Nodal disease | ||||
| N0 (RL) | ||||
| N1 | <0.001 | 2.779 | 2.562 | 3.014 |
| Nx | 0.006 | 1.249 | 1.066 | 1.464 |
| Type of surgery | ||||
| Less than lobectomy (RL) | ||||
| Lobectomy/bilobectomy | <0.001 | 0.296 | 0.272 | 0.321 |
| Pneumonectomy | <0.001 | 0.276 | 0.232 | 0.329 |
| Surgery, NOS | 0.243 | 1.307 | 0.834 | 2.049 |
| Nodes examined | ||||
| 0 (RL) | ||||
| 1–9 | <0.001 | 0.596 | 0.542 | 0.655 |
| 10+ | <0.001 | 0.390 | 0.347 | 0.439 |
| FNA | 0.073 | 1.566 | 0.959 | 2.557 |
| Sampling, NOS | 0.001 | 0.466 | 0.300 | 0.724 |
| Dissection, NOS | <0.001 | 0.453 | 0.368 | 0.557 |
| Unknown | <0.001 | 0.674 | 0.554 | 0.819 |
| Chemotherapy | ||||
| Not received (RL) | ||||
| Received | <0.001 | 5.229 | 4.855 | 5.632 |
CI confidence interval, FNA fine needle aspiration, NOS not otherwise specified, OR odds ratio, RL reference level