Biological samples |
|
See Table S1 for a complete list of all human samples used in the current study |
N/A |
N/A |
See Table S5 for a complete list of all macaque and mouse samples used in the current study |
N/A |
N/A |
|
Deposited data |
|
Raw RNA-seq & WGS data – DLPFC |
https://www.synapse.org
|
syn21557948 |
Raw RNA-seq data – Cerebrum & Cerebellum |
https://www.ebi.ac.uk/arrayexpress/
|
E-MTAB-6814 |
Raw RNA-seq data – Cortex and normal aging |
https://www.synapse.org
|
syn7416949 |
Raw RNA-seq data – hESC differentiation |
https://www.ncbi.nlm.nih.gov/geo/
|
GSE56796 |
Raw RNA-seq data – hiPSC differentiation |
https://www.ncbi.nlm.nih.gov/bioproject/
|
PRJNA596331 |
Raw RNA-seq data – Rhesus Macaque |
https://www.ncbi.nlm.nih.gov/bioproject/
|
PRJNA448973 |
Raw RNA-seq data – Mouse |
https://www.ncbi.nlm.nih.gov/sra
|
SRP055008 |
Processed RNA editing calls – DLPFC, Cerebrum & Cerebellum |
https://www.synapse.org
|
syn26434508 |
|
Software and algorithms |
|
Code used to process data |
This paper |
https://doi.org/10.5281/zenodo.7108745
|
STAR v2.7.3 |
Dobin etal., 201377
|
https://github.com/alexdobin/STAR
|
REDItools v2.0 |
Flati et al., 202040
|
https://github.com/BioinfoUNIBA/REDItools2
|
JACUSA2 |
Piechotta et al., 202241
|
https://github.com/dieterich-lab/JACUSA2
|
SAMtools v1.16 |
Harvard Medical School, Boston |
https://github.com/samtools/samtools
|
Picard v.2.22.3 |
Broad Institute, Boston |
https://github.com/broadinstitute/picard/
|
ANNOVAR (Oct 24 2019) |
Wang etal., 201078
|
https://github.com/WGLab/doc-ANNOVAR
|
Phastcons v.3.15 |
Hubisz et al., 201179
|
https://bioconductor.org/packages/release/data/annotation/html/phastCons100way.UCSC.hg38.html
|
Mice: Multivariate Imputation by Chained Equations v.3.14.0 |
Buuren etal., 201080
|
https://cran.r-project.org/web/packages/mice/index.html
|
RNAEditingIndexer v.1 |
Roth etal., 201939
|
https://github.com/a2iEditing/RNAEditingIndexer
|
bMINDv 0.3.2 |
Wang etal., 202181
|
https://github.com/randel/MIND
|
limma v.3.36.3 |
N/A |
https://bioconductor.org/packages/release/bioc/html/limma.html
|
ToppGene Suite software |
Chen et al., 200982
|
https://toppgene.cchmc.org/enrichment.jsp
|
SynGO |
Koopmans et al., 201983
|
https://www.syngoportal.org
|
GeneOverlap v.1.32.0 |
Shen et al., 202284
|
https://bioconductor.org/packages/release/bioc/html/GeneOverlap.html
|
RNA hyper-editing v.1 |
Porath et al., 201421
|
https://github.com/hagitpt/Hyper-editing
|
miRANDA v.3.3 |
Betel etal., 201085
|
https://bioweb.pasteur.fr/packages/pack@miRanda@3.3a
|
SpliceAI v.1.3.1 |
Jaganathan et al., 201986
|
https://github.com/Illumina/SpliceAI
|
SIRI v.1 |
Yeom etal., 202187
|
https://github.com/Xinglab/siri
|
Viennarna v.2.4.12 (RNAfold) |
Hofacker et al., 200388
|
https://github.com/ViennaRNA/ViennaRNA
|
fastQTL v.2.184 |
Ongen et al., 201689
|
https://github.com/francois-a/fastqtl
|
Coloc v2 |
Dobbyn etal., 201890
|
https://github.com/Stahl-Lab-MSSM/coloc2
|